Disease Models-Contract Research
Probetex Inc. provides contract services for drug discovery in renal and other organ disease models. We provide a menu-driven approach to meet our customers requirements. Blood, urine, and kidney tissue, isolated glomeruli or tubules can be obtained, processed and analyzed by Probetex or sent directly to the client. Services include drug testing in animal models, renal function tests (creatinine, blood urea nitrogen, urine protein) tissue processing for paraffin embedment and staining (H&E, PAS, etc) fresh frozen tissue for immunohistochemistry, electron microscopy, image analysis, and tissue lysates for Western analysis. Projects are custom assembled to meet each customer's unique requirements utilizing a team of experts specializing in disease models. (see publications)
Custom renal, cardiovascular hepatic, and pulmonary models are also available.
Comprehensive histopathology support available (more)
Probetex assists clients in the development of rare disease models
(See our vasculitis initiative)
Custom renal, cardiovascular hepatic, and pulmonary models are also available.
Comprehensive histopathology support available (more)
Probetex assists clients in the development of rare disease models
(See our vasculitis initiative)
Classic Kidney Disease Models
Anti-GBM Immune-Mediated Glomerulonephritis.
Anti-Rat Glomeruli (GBM)
Anti-Rat Glomeruli (GBM)
- Mesangial Proliferation
- Inflammatory Cell Vasculitis
- Glomerulosclerosis
- Renal Fibrosis
Membranous Glomerulonephritis
Anti-Rat Fx1A Serum (Heymann Nephritis)
Anti-Rat Fx1A Serum (Heymann Nephritis)
- Sub-epithelial immune complex disease
- Podocytopathy
- Proteinuria
Mesangioproliferative Glomerulonephritis
Anti-Rat Thymocyte (Thy-1)
Disease model description
Anti-Rat Thymocyte (Thy-1)
- Mesangial Migration & Proliferation
- Mesangial Matrix Synthesis
- Inflammatory Cell Infiltration
Disease model description
Diabetic Nephropathy (Type 1)
Streptozotocin-Induced Glomerulopathy
Streptozotocin-Induced Glomerulopathy
- Mesangial Matrix Expansion
- Podocytopathy
- Macrophage Infiltration
Expertise in Over 20 Additional Models of Renal Disease
- Acute Kidney Injury (AKI) Models
- Chronic Kidney Disease (CKD) Models
- Model Consultation
Models of Systemic Disease
Custom Research Models to Suit Your Requirements
Acute and Chronic Diseases
Acute and Chronic Diseases
- Heart
- Lung
- Liver